| NNancy NovotnyMadlax (voice) | Madlax (voice) |
| CChris PattonHimself | Himself |
 Luci ChristianMargaret Burton (voice) | Margaret Burton (voice) |
| JJay HickmanSSS (voice) | SSS (voice) |
| CChristine McPeters AutenLimelda Jorg (voice) | Limelda Jorg (voice) |
 Vic MignognaCarrossea Doon (voice) | Carrossea Doon (voice) |
| KKira Vincent-DavisElenore Baker (voice) | Elenore Baker (voice) |
| KKelly ManisonVanessa Rene (voice) | Vanessa Rene (voice) |
| HHilary HaagForked Fem | Forked Fem |
 Monica RialJunk Food Junkie | Junk Food Junkie |
| AAdam JonesJunk Food Junkie | Junk Food Junkie |
| DDavid WilliamsDLW | DLW |
| CCharles C. CampbellMargaret's Director | Margaret's Director |
| GGary SteinmanFeet in Toilet | Feet in Toilet |
 Jessica BooneToo-Much-Caffeine Girl | Too-Much-Caffeine Girl |
| BBlake ShepardHimself | Himself |
| KKyle JonesHands / Bootallion | Hands / Bootallion |
| JJonathan BrandsHands / Bootallion / Rubber Necker | Hands / Bootallion / Rubber Necker |
| AAnthony BenevidasHands / Bootallion / Rubber Necker | Hands / Bootallion / Rubber Necker |
| JJacob A. GragardHands / Rubber Necker | Hands / Rubber Necker |
| MMike YantoscaHands | Hands |
 Tiffany GrantHands | Hands |
| EEden BarreraBootallion | Bootallion |
 John SwaseyBootallion | Bootallion |
 Chris AyresBootallion | Bootallion |
| DDaniel ScruggsRubber Necker | Rubber Necker |
| EEddie ShannonRubber Necker | Rubber Necker |
| LLeo PedemonteRubber Necker | Rubber Necker |
| JJon DuckworthRubber Necker | Rubber Necker |