A woman embarks on a journey alone across the United States after fleeing from her violent husband.
| Actor | Role |
|---|---|
 Diane KrugerRomy | Romy |
 Norman ReedusDiego | Diego |
 Gilles LelloucheRichard | Richard |
 Lena DunhamBillie | Billie |
 Q'orianka KilcherMissy | Missy |
 Lou Diamond PhillipsDuane | Duane |
 Joshua JacksonInspecteur Ruther | Inspecteur Ruther |
 Laurene LandonCharlene | Charlene |
 John RobinsonNight Biker | Night Biker |
 Michelle LombardoHelen | Helen |
| TTrevor PetersonJoe | Joe |
| SSasha Perl-RaverBar Girl - Kelly | Bar Girl - Kelly |
 Vanessa VillalovosGloria | Gloria |
 Daniel PoloMickey | Mickey |
 Andrew BryniarskiJesse | Jesse |
 Sal Velez Jr.CHP Officer | CHP Officer |
 Raf MauroMotel Clerk | Motel Clerk |
 Diana YanezBuckshot Diner Waitress | Buckshot Diner Waitress |
| KKrista HazelwoodMexican Diner Waitress | Mexican Diner Waitress |
| MMicah SchifmanLas Vegas Clerk | Las Vegas Clerk |
 Van EppersonCar Dealer | Car Dealer |
 Joseph RunningfoxMilitant Indian | Militant Indian |
 Miles HaydenYoung Diego | Young Diego |
| JJeff PodgurskiCowboy Stuntman | Cowboy Stuntman |
 Roberto MedinaDoctor | Doctor |