Skippy, the mischievous son of a wealthy doctor, meets Sooky in poverty-ridden Shantytown, and together they try to save Sooky's pet from a cruel dogcatcher.
| Actor | Role |
|---|---|
 Jackie CooperSkippy Skinner | Skippy Skinner |
 Robert CooganSooky | Sooky |
 Mitzi GreenEloise | Eloise |
 Jackie SearlSidney | Sidney |
 Willard RobertsonHerbert Skinner | Herbert Skinner |
 Enid BennettEllen Skinner | Ellen Skinner |
 Donald HainesHarley Nubbins | Harley Nubbins |
 Helen Jerome EddyMrs. Wayne | Mrs. Wayne |
| BBeaudine AndersonBoy | Boy |
 Dannie Mac GrantBoy | Boy |
| DDouglas HaigBoy | Boy |
| PPayne B. JohnsonBoy | Boy |
| BBuddy McDonaldBoy | Boy |
| CCarl R. BotefuhrSkippy Skinner (age 3) | Skippy Skinner (age 3) |
 Jack Rube CliffordDog-Catcher Nubbins | Dog-Catcher Nubbins |
 Guy OliverDad Burkey | Dad Burkey |