The boys are a dentist and his assistant traveling to the Old West to open a new practice. Once in town, they buy a business--only to wake up the next day and see that the entire population of this bustling town had left for the California gold fields early that morning! Then, they discover an evil plot to sell out these settlers to some hostile Indians, so they spring to the rescue.
| Actor | Role |
|---|---|
 Bert WheelerRoy Banks | Roy Banks |
 Robert WoolseyDr. Philip 'Painless' Pennington | Dr. Philip 'Painless' Pennington |
 Dorothy LeeMary Blake | Mary Blake |
 Harry WoodsHank Bewley | Hank Bewley |
 Ethan LaidlawTrigger | Trigger |
 Chief ThunderbirdChief Cyclone | Chief Cyclone |
 Delmar WatsonMartin | Martin |
 Richard AlexanderJohn Little | John Little |
| PPhilip ArmentaIndian | Indian |
 Harry BernardProspector | Prospector |
 Willie BestExcitement | Excitement |
 Maurice BlackBandit with Toothache | Bandit with Toothache |
 Stanley BlystoneCavalry Captain | Cavalry Captain |
 Tommy BondStudent | Student |
| JJoan BreslauStudent | Student |
 Ivan ChristyBandit | Bandit |
| JJack CurtisPioneer | Pioneer |
 Anna DemetrioHumming Bird | Humming Bird |
 Dick ElliottMayor Culpepper | Mayor Culpepper |
 Mabel ForrestPioneer | Pioneer |
 Olin FrancisPioneer | Pioneer |
| FFrank HammondBarker | Barker |
 Edward HearnMark - Martin's Brother | Mark - Martin's Brother |
 John InceBit | Bit |
 Jane KeckleyBit | Bit |
| JJoe Smith MarbaBit | Bit |
 Carl MathewsIndian | Indian |
 Nelson McDowellHorse Trader | Horse Trader |
 Ivor McFaddenPioneer | Pioneer |
 Lafe McKeePioneer | Pioneer |