 Andrew GarfieldRodrigues | Rodrigues |
 Adam DriverGarupe | Garupe |
 Liam NeesonFerreira | Ferreira |
 Tadanobu AsanoInterpreter | Interpreter |
 Ciarán HindsFather Valignano | Father Valignano |
 Issey OgataOld Samurai / Inoue | Old Samurai / Inoue |
 Shinya TsukamotoMokichi | Mokichi |
 Yoshi OidaIchizo | Ichizo |
 Yosuke KubozukaKichijiro | Kichijiro |
| KKaoru EndōUnzen Samurai (Uneme) | Unzen Samurai (Uneme) |
| DDiego CalderónPrisoner Augustinian Friar #2 | Prisoner Augustinian Friar #2 |
| RRafael KadingPrisoner Augustinian Friar #1 | Prisoner Augustinian Friar #1 |
| MMatthew BlakePrisoner Franciscan Friar | Prisoner Franciscan Friar |
| BBenoit MassePrisoner Augustinian Friar #3 | Prisoner Augustinian Friar #3 |
 Tetsuya IgawaPrisoner Japanese Jesuit | Prisoner Japanese Jesuit |
 Shi LiangChinese Businessman (Mr. Chun) | Chinese Businessman (Mr. Chun) |
| PPantaTomogi Villager #1 (Yohei) | Tomogi Villager #1 (Yohei) |
 Takuya MatsunagaTomogi Villager #2 (Toukichi) | Tomogi Villager #2 (Toukichi) |
 Miho HaritaIchizo's Wife (Tomi) | Ichizo's Wife (Tomi) |
 Hairi KatagiriTomogi Woman (Tsune) | Tomogi Woman (Tsune) |
| MMasayuki YamadaTomogi Husband (Kasuke) | Tomogi Husband (Kasuke) |
 MichiéTomogi Wife (Mitsu) | Tomogi Wife (Mitsu) |
 Hiroko IsayamaTomogi Village Woman (Hiro) | Tomogi Village Woman (Hiro) |
 Yutaka MishimaGoto Man #1 (Kuro) | Goto Man #1 (Kuro) |
 Yasunari TakeshimaGoto Man #2 (Haku) | Goto Man #2 (Haku) |
 Yuri IshizakaKichijiro Sister at Stake (Tae) | Kichijiro Sister at Stake (Tae) |
 Ryo SatoKichijiro Sister #2 (Hisa) | Kichijiro Sister #2 (Hisa) |
| RRuo SatôKichijiro Father (Kichizo) | Kichijiro Father (Kichizo) |
 Yoriko DoguchiKichijiro Mother (Naka) | Kichijiro Mother (Naka) |
 Kisetsu FujiwaraKichijiro Brother #2 (Kichita) | Kichijiro Brother #2 (Kichita) |
