 Drew MasseySid / Stack (voice) | Sid / Stack (voice) |
 Misty RosasSid | Sid |
 Alice DinneanGabriela (voice) / Susie / Zeke / Mom (voice) / Miao Hu (voice) / QT9 (voice) | Gabriela (voice) / Susie / Zeke / Mom (voice) / Miao Hu (voice) / QT9 (voice) |
 John Munro CameronGabriela / Dr. Bonabodon / Dad | Gabriela / Dr. Bonabodon / Dad |
 Allan TrautmanYangyang (voice) / Gerald / Dad | Yangyang (voice) / Gerald / Dad |
| AAlon WilliamsYangyang / Gerald / Zeke | Yangyang / Gerald / Zeke |
 Matthew Yang KingYangyang | Yangyang |
 Julianne BuescherNiuNiu / Grandma / May (voice) | NiuNiu / Grandma / May (voice) |
 Dana WoodsNiuNiu / Grandma / Miao Hu / May | NiuNiu / Grandma / Miao Hu / May |
 Christopher LloydDr. Bonabodon (voice) | Dr. Bonabodon (voice) |
 Bruce LanoilDr. Bonabodon (face) / Bobbybot (voice) / Zeke / Ira (voice) / Zippa (voice) | Dr. Bonabodon (face) / Bobbybot (voice) / Zeke / Ira (voice) / Zippa (voice) |
 Victor YerridGerald / Dad / Popo (voice) | Gerald / Dad / Popo (voice) |
 Donna KimballSusie / Zeke / PA Announcer / Pinki (voice) | Susie / Zeke / PA Announcer / Pinki (voice) |
 Sonya LeslieSusie / Mom | Susie / Mom |
| KKristin CharneyDr. Cordova | Dr. Cordova |
 America FerreraDr. Cordova (voice) | Dr. Cordova (voice) |
| MMichelan SistiDr. Cordova | Dr. Cordova |
