 Mike MyersShrek (voice) | Shrek (voice) |
 Eddie MurphyDonkey (voice) | Donkey (voice) |
 Cameron DiazPrincess Fiona (voice) | Princess Fiona (voice) |
 Antonio BanderasPuss in Boots (voice) | Puss in Boots (voice) |
 Julie AndrewsQueen Lillian (voice) | Queen Lillian (voice) |
 John CleeseKing Harold (voice) | King Harold (voice) |
 Rupert EverettPrince Charming (voice) | Prince Charming (voice) |
 Eric IdleMerlin (voice) | Merlin (voice) |
 Justin TimberlakePrince Artie (voice) | Prince Artie (voice) |
 Susanne BlakesleeEvil Queen (voice) | Evil Queen (voice) |
 Cody CameronPinocchio / Three Pigs (voice) | Pinocchio / Three Pigs (voice) |
 Larry KingDoris (voice) | Doris (voice) |
 Christopher KnightsBlind Mice / Heckler / Evil Tree #2 / Guard #2 (voice) | Blind Mice / Heckler / Evil Tree #2 / Guard #2 (voice) |
 John KrasinskiLancelot (voice) | Lancelot (voice) |
 Ian McShaneCaptain Hook (voice) | Captain Hook (voice) |
 Cheri OteriSleeping Beauty / Actress (voice) | Sleeping Beauty / Actress (voice) |
 Regis PhilbinMabel (voice) | Mabel (voice) |
 Amy PoehlerSnow White (voice) | Snow White (voice) |
 Megan HiltySnow White (singing voice) | Snow White (singing voice) |
 Seth RogenShip Captain (voice) | Ship Captain (voice) |
 Maya RudolphRapunzel (voice) | Rapunzel (voice) |
 Amy SedarisCinderella (voice) | Cinderella (voice) |
 Conrad VernonGingerbread Man / Rumplestiltskin / Headless Horseman (voice) | Gingerbread Man / Rumplestiltskin / Headless Horseman (voice) |
 Aron WarnerWolf (voice) | Wolf (voice) |
| JJasper Johannes AndrewsOgre Baby (voice) | Ogre Baby (voice) |
 Guillaume AretosRaul (voice) | Raul (voice) |
 Kelly AsburyMaster of Ceremonies / Fiddlesworth (voice) | Master of Ceremonies / Fiddlesworth (voice) |
| ZZachary James BernardOgre Baby (voice) | Ogre Baby (voice) |
| AAndrew BirchEvil Tree #1 (voice) | Evil Tree #1 (voice) |
 Sean BishopDrivers Ed Instructor / Hall Monitor / Teacher (voice) | Drivers Ed Instructor / Hall Monitor / Teacher (voice) |
