She Don't Fade chronicles the sexual pursuits of Shae Clarke, an African American lesbian. Clarke, played by Dunye herself, defines and readily demonstrates her "new approach to women."
| Actor | Role |
|---|---|
 Cheryl DunyeCheryl / Shae Clarke | Cheryl / Shae Clarke |
| PPaula CronanPaula | Paula |
| ZZoie StraussZoie | Zoie |
| WWanda FreemanNot listed | Not listed |
 Gail LloydNot listed | Not listed |
| PPin MartinNot listed | Not listed |
| JJennifer OzarowNot listed | Not listed |
| HHeather HassingerNot listed | Not listed |
| KK. Brent HillNot listed | Not listed |
| BBarbara KigoziNot listed | Not listed |
| LLaura RauNot listed | Not listed |