Karen and Jack met in a mental hospital and fell in love. They set out to follow what Jack thinks is his destiny: killing Elvis Presley.
| Actor | Role |
|---|---|
 Emily BrowningKaren Bird | Karen Bird |
 Luke GrimesJack Blueblood | Jack Blueblood |
 Avan JogiaTeijo Littlefoot | Teijo Littlefoot |
 Ashley GreenePriscilla Presley | Priscilla Presley |
 Burt ReynoldsNarrator | Narrator |
 John Carroll LynchColonel Tom Parker | Colonel Tom Parker |
 Ron LivingstonElvis Presley | Elvis Presley |
 Tatanka MeansOfficer Gingrass | Officer Gingrass |
 Paul RaeRandyll | Randyll |
 Alyvia Alyn LindLisa Marie Presley | Lisa Marie Presley |
 Kate ButlerKaren's Mother | Karen's Mother |
 Trevante RhodesMike | Mike |
 Amanda AdayGladys Presley | Gladys Presley |
| JJoseph WiseYoung Jack | Young Jack |
 Jade PettyjohnYoung Karen | Young Karen |
 Echo KellumHepcat | Hepcat |
 Reiley McClendon1950's Elvis | 1950's Elvis |
 Rob ZabreckyToby | Toby |
| KKate KriegerNot listed | Not listed |
 Daniel SpinkGuru | Guru |
 Dillon Daniel MutyabaJerome | Jerome |
| KKristen KassingerLauren | Lauren |
| SSarah Noble PeckMary | Mary |
| ZZoe VanceLoretta Blueblood | Loretta Blueblood |
| JJasmin RadibratovicJasmine | Jasmine |
 Michael CiminoYoung Teijo | Young Teijo |
 Alan TudykDr. Sanborne | Dr. Sanborne |