 Marlene DietrichShanghai Lily | Shanghai Lily |
 Clive BrookCaptain Donald 'Doc' Harvey | Captain Donald 'Doc' Harvey |
 Anna May WongHui Fei | Hui Fei |
 Warner OlandMr. Henry Chang | Mr. Henry Chang |
 Eugene PalletteSam Salt | Sam Salt |
 Lawrence GrantReverend Carmichael | Reverend Carmichael |
| LLouise Closser HaleMrs. Haggerty | Mrs. Haggerty |
 Gustav von SeyffertitzEric Baum | Eric Baum |
 Émile ChautardMajor Lenard | Major Lenard |
 George BlagoiMinor Role (uncredited) | Minor Role (uncredited) |
 Leonard CareyCarey (uncredited) | Carey (uncredited) |
| GGeorge ChungChinese Soldier (uncredited) | Chinese Soldier (uncredited) |
 Wong ChungChinese Officer Checking Passports (uncredited) | Chinese Officer Checking Passports (uncredited) |
| JJack DeeryBritish Officer at Shanghai (uncredited) | British Officer at Shanghai (uncredited) |
 Herbert EvansBritish Railway Officer (uncredited) | British Railway Officer (uncredited) |
 Willie FungTrain Engineer (uncredited) | Train Engineer (uncredited) |
| TTom GubbinsChinese Officer (uncredited) | Chinese Officer (uncredited) |
| FForrester HarveyPeiping Ticket Agent (uncredited) | Peiping Ticket Agent (uncredited) |
 Claude KingMr. Albright (uncredited) | Mr. Albright (uncredited) |
 James B. LeongA Rebel (uncredited) | A Rebel (uncredited) |
 Miki MoritaChinese Officer (uncredited) | Chinese Officer (uncredited) |
| MMinoru NishidaLi Fung (uncredited) | Li Fung (uncredited) |
 Victor WongChinese Officer (uncredited) | Chinese Officer (uncredited) |
| UUra MitaChinese Woman (uncredited) | Chinese Woman (uncredited) |
