There's a new Muppet on the block named Dani who suffers from Asthma. With the help of Luis, they both teach Elmo and Rosita about childhood Asthma through example and music.
| Actor | Role |
|---|---|
| GGabriel VelezDani the Asthmatic Muppet (voice) | Dani the Asthmatic Muppet (voice) |
 Carmen OsbahrRosita (voice) | Rosita (voice) |
 Kevin ClashElmo (voice) | Elmo (voice) |
 Emilio DelgadoLuis | Luis |
 Pam ArcieroGrungetta (voice) | Grungetta (voice) |
 Alice DinneanAdditional Muppets (voice) | Additional Muppets (voice) |
 Matt VogelNot listed | Not listed |
 John TartagliaNot listed | Not listed |
 Alison BartlettGina Jefferson | Gina Jefferson |
 Lisa BuckleyNot listed | Not listed |
 John E. KennedyNot listed | Not listed |