Agent Joaquin recalls his latest mission while lying wounded in an ambulance: Joaquin has infiltrated into a band of smugglers. When the villains learn the truth about him, they kidnap Jouqin's fiancee. Santo comes to her rescue and fights the band.
| Actor | Role |
|---|---|
 Joaquín CorderoJoaquín | Joaquín |
 Gina RomandIrma | Irma |
 Enrique ZambranoTeniente Zambrano | Teniente Zambrano |
 Jorge MarxJamie | Jamie |
 Fernando OsésEnrique | Enrique |
| JJuanito TrembleNot listed | Not listed |
| CCarlos OrihuelaNot listed | Not listed |
| MMario TexasNot listed | Not listed |
| RRoberto MonasterioNot listed | Not listed |
| SSilvia PenichetNot listed | Not listed |
| AAldo AguirreNot listed | Not listed |
| VVeny GonzalezNot listed | Not listed |
| MMariano CastroNot listed | Not listed |
| EEloy RodríguezNot listed | Not listed |
 El SantoSanto, el Enmascarado de Plata | Santo, el Enmascarado de Plata |
| TTrio Servando DiazNot listed | Not listed |
| LLos Romero y EstelitaNot listed | Not listed |