Santa is a beautiful and very humble young girl living in Chimalistac, a small and quiet spot south of the 1930's Mexico City. After Santa is cheated by arrogant soldier Marcelino, she's rejected by her family and friends and expelled of Chimalistac. Santa finds shelter in a whorehouse and becomes a cinic and bitter woman, mistreated by bullfighter "Jarameno" and silently loved by blind pianist Hipólito.
| Actor | Role |
|---|---|
 Lupita TovarSanta | Santa |
 Carlos OrellanaHipólito | Hipólito |
 Juan José Martínez CasadoJarameño | Jarameño |
 Donald ReedMarcelino | Marcelino |
 Antonio R. FraustoFabián | Fabián |
| MMimí DerbaDoña Elvira | Doña Elvira |
| RRosita ArriagaSanta's Mother | Santa's Mother |
 Joaquín BusquetsEsteban | Esteban |
| FFeliciano RuedaDrunk at brothel | Drunk at brothel |
| JJorge PeónGenarillo | Genarillo |
 Alberto MartíJarameño's friend | Jarameño's friend |
| RRicardo CartiDoctor | Doctor |
 Sofía ÁlvarezProstitute 1 | Prostitute 1 |
| RRosa CastroProstitute 2 | Prostitute 2 |
| NNena BetancourtSinger | Singer |
| JJorge MarrónNot listed | Not listed |
| Carlos BocanegraNot listed | Not listed |
 Fernando A. RiveroNot listed | Not listed |
| LLupita GallardoProstitute 3 | Prostitute 3 |
 Ismael RodríguezNot listed | Not listed |
 Raúl de AndaNot listed | Not listed |
| PParkey HussianNot listed | Not listed |
| CCube BonifantNot listed | Not listed |