While a terrorist epidemy strikes the world leaders, the commissaire San-Antonio and his partner, the lieutenant Bérurier, have to escort the French ambassador in a British hotel. But after a negligence of Bérurier (one more little sex affair...), San-Antonio witnessed, helpless, to the ambassador's abduction, organized by a gorgeous Italian girl. Back to Paris, San-Antonio is dismissed by the police chief, Achille Hachille. A real godsend for Bérurier, who get promoted... But soon, the situation degenerates, when the president of the Republic mysteriously disappears. Immediate reaction from Police Minister : San-Antonio is the only one who can save the day. He has 48 hours and a secret squad to find the president. At the Elysée, San-Antonio finds Bérurier, the official investigator. But now, it's every man for himself : who will be the first to find the President ?
| Actor | Role |
|---|---|
 Gérard Lanvinle commissaire San-Antonio | le commissaire San-Antonio |
 Gérard Depardieul'inspecteur Bérurier | l'inspecteur Bérurier |
 Barbara SchulzMarianne | Marianne |
 Luis RegoPinaud | Pinaud |
 Michel GalabruAchille | Achille |
 Ériq EbouaneyJérémie Blanc | Jérémie Blanc |
 Robert HosseinLe ministre de l'intérieur / The Minister | Le ministre de l'intérieur / The Minister |
 Jérémie RenierToinet | Toinet |
 Michèle BernierBerthe | Berthe |
 Jean-Roger MiloMathias | Mathias |
 Patrick MédioniVan Gogh | Van Gogh |
| BBill BarclayL'Écossais | L'Écossais |
 Guilhem PellegrinLe secrétaire de l'Elysée | Le secrétaire de l'Elysée |
 Lucy HarrisonLa masseuse | La masseuse |
 Marc FaureSon Excellence | Son Excellence |
| MMarie-Thérèse ArèneFélicie | Félicie |
 Nick HobbsLord Kensington | Lord Kensington |
 Valeria GolinoL'Italienne | L'Italienne |
 Vanessa GuedjLa soubrette | La soubrette |