Sabrina goes to Rome, with Salem stowaway-ed in her backpack, to free her 16th-century aunt Sophia who was banished for divulging her powers to a non-witch.
| Actor | Role |
|---|---|
 Melissa Joan HartSabrina / Sophie | Sabrina / Sophie |
 Eddie MillsPaul | Paul |
 Tara StrongGwen | Gwen |
| JJames FieldsTravis | Travis |
 Eric AlexanderAlberto | Alberto |
 Nick BakaySalem Saberhagen (voice) | Salem Saberhagen (voice) |
 Richard Steven HorvitzStonehenge (voice) | Stonehenge (voice) |
| FFrancesco MazziniMercutio | Mercutio |
| EEvelyn FurtakMrs. Guadagno | Mrs. Guadagno |
| RRobert SteinerRoberto | Roberto |
 Stefano Maria MioniTaxi Driver | Taxi Driver |
 Paolo GiovannucciStatue of David | Statue of David |