In 1868, after the Bakumatsu war ends, the ex-assassin Kenshin Himura traverses Japan with an inverted sword, to defend the needy without killing.
| Actor | Role |
|---|---|
 Takeru SatohKenshin Himura | Kenshin Himura |
 Emi TakeiKaoru Kamiya | Kaoru Kamiya |
 Koji KikkawaUdo Jine | Udo Jine |
 Yu AoiMegumi Takani | Megumi Takani |
 Munetaka AokiSanosuke Sagara | Sanosuke Sagara |
 Go AyanoGein | Gein |
 Genki SudoBanjin Inui | Banjin Inui |
 Taketo TanakaYahiko Myojin | Yahiko Myojin |
 Eiji OkudaAritomo Yamagata | Aritomo Yamagata |
 Yosuke EguchiHajime Saito | Hajime Saito |
 Teruyuki KagawaKanryu Takeda | Kanryu Takeda |
 Kaoru HirataTae Sekihara | Tae Sekihara |
 Mei NaganoTsubame Sanjo | Tsubame Sanjo |
 Yusuke HirayamaOlder Brother | Older Brother |
 Motoki FukamiYounger Brother | Younger Brother |
 Daisuke HondaKodama | Kodama |
| KKotaro OkamotoKikuchi | Kikuchi |
 Toshihiro YashibaKubo's Husband | Kubo's Husband |
 Atsuko AnamiKubo's Wife | Kubo's Wife |
 Motoki OchiaiMizushima | Mizushima |
| RRyôta MatsushimaNot listed | Not listed |
 Masataka KubotaAkira Kiyosato | Akira Kiyosato |
 Ichirôta MiyakawaKogoro Katsura | Kogoro Katsura |
 Ryuhei HigashiyamaSoldier 4 | Soldier 4 |
 Masashi ArifukuOriental Doctor | Oriental Doctor |
| YYuta KubaNot listed | Not listed |