When the South loses the war, Confederate veteran O'Meara goes West, joins the Sioux, takes a wife and refuses to be an American but he must choose a side when the Sioux go to war against the U.S. Army.
| Actor | Role |
|---|---|
 Rod SteigerPvt. O'Meara | Pvt. O'Meara |
 Sara MontielYellow Moccasin | Yellow Moccasin |
 Brian KeithCaptain Clark | Captain Clark |
 Ralph MeekerLieutenant Driscoll | Lieutenant Driscoll |
 Jay C. FlippenWalking Coyote | Walking Coyote |
 Charles BronsonBlue Buffolo | Blue Buffolo |
 Olive CareyMrs O'Meara | Mrs O'Meara |
 H.M. WynantCrazy Wolf | Crazy Wolf |
 Neyle MorrowLt. Stockwell | Lt. Stockwell |
 Frank De KovaRed Cloud (as Frank De Kova) | Red Cloud (as Frank De Kova) |
 Tim McCoyGen. Allen (as Colonel Tim McCoy) | Gen. Allen (as Colonel Tim McCoy) |
 Stuart RandallCol. Taylor | Col. Taylor |
| FFrank WarnerBanjo Playing Singer | Banjo Playing Singer |
| BBilly MillerSilent Tongue | Silent Tongue |
 Chuck HaywardCorporal | Corporal |
 Chuck RobersonSergeant | Sergeant |
| GGeorge RossArcher (uncredited) | Archer (uncredited) |
| RRay StevensMan in Boat (uncredited) | Man in Boat (uncredited) |