ROH 15th Anniversary will feature professional wrestling matches that involved wrestlers from pre-existing scripted feuds or storylines that play out on ROH's television program, Ring of Honor Wrestling. Wrestlers will portray heroes (faces) or villains (heels) as they follow a series of events that build tension and culminate in a wrestling match or series of matches.
| Actor | Role |
|---|---|
 Jamie WhiteNot listed | Not listed |
 Kenny D. LayneNot listed | Not listed |
 Caleb DewallSilas Young | Silas Young |
 Frank GerdelmanNot listed | Not listed |
 Stephen WoltzHangman Page | Hangman Page |
 Josh HarterChris Sabin | Chris Sabin |
 Jamar ShipmanJay Lethal | Jay Lethal |
 Robert Anthony FishNot listed | Not listed |
 Matthew MarinelliMatt Taven | Matt Taven |
 Brett GiehlDalton Castle | Dalton Castle |
 Mark LoMonacoBully Ray | Bully Ray |
 Mark PughMark Briscoe | Mark Briscoe |
 Jamin PughJay Briscoe | Jay Briscoe |
 Raymond RoweNot listed | Not listed |
 Todd SmithHanson | Hanson |
 Harry SmithDavey Boy Smith Jr. | Davey Boy Smith Jr. |
 Matt HardyNot listed | Not listed |
 Jeff HardyNot listed | Not listed |
 John Raymond RiveraRocky Romero | Rocky Romero |
 Gregory MarasciuloBeretta | Beretta |
 Matthew MassieMatt Jackson | Matt Jackson |
 Nicholas MassieNick Jackson | Nick Jackson |
 Austin JenkinsAdam Cole | Adam Cole |
 Daniel CovellNot listed | Not listed |