When a radio falls from the sky into the hands of a wide-eyed Tibetan Mastiff, he leaves home to fulfill his dream of becoming a musician, setting into motion a series of completely unexpected events.
| Actor | Role |
|---|---|
 Luke WilsonBodi (voice) | Bodi (voice) |
 Suzy Eddie IzzardAngus Scattergood (voice) | Angus Scattergood (voice) |
 J.K. SimmonsKhampa (voice) | Khampa (voice) |
 Lewis BlackLinnux (voice) | Linnux (voice) |
 Kenan ThompsonRiff (voice) | Riff (voice) |
 Mae WhitmanDarma (voice) | Darma (voice) |
 Jorge GarciaGermur (voice) | Germur (voice) |
 Matt DillonTrey (voice) | Trey (voice) |
 Sam ElliottFleetwood Yak (voice) | Fleetwood Yak (voice) |
| WWill FinnFloyd / Carl (voice) | Floyd / Carl (voice) |
 Ash BrannonIan (voice) | Ian (voice) |
| LLiza RichardsonRadio DJ (voice) | Radio DJ (voice) |
 Julie CraigAdditional Voices (voice) | Additional Voices (voice) |
| DDeng FengAdditional Voices (voice) | Additional Voices (voice) |
 Kellen GoffRock Show Announcer / Additional Voices (voice) | Rock Show Announcer / Additional Voices (voice) |
 Jennifer HaleAdditional Voices (voice) | Additional Voices (voice) |
 Maddie TaylorAdditional Voices (voice) | Additional Voices (voice) |