On a quest to fulfill a friend's last wish, Joe takes to the desert road on his 1957 Harley-Davidson. Joined by wannabe biker Sam, Joe journeys from Los Angeles to Nevada, meeting all sorts of characters along the way.
| Actor | Role |
|---|---|
 John DoeJoe Mosley | Joe Mosley |
 Adam HorovitzSam | Sam |
 Jennifer BalgobinMs. Labia Mirage | Ms. Labia Mirage |
 David Anthony MarshallDave Coleman | Dave Coleman |
 David CarradineOthello Jones | Othello Jones |
 Arlo GuthrieHarvey | Harvey |
 Don CheadleHappy Days Manager | Happy Days Manager |
 John CusackCaspar | Caspar |
 Timothy LearySalvadore | Salvadore |
 Stephen TobolowskyRanger Bob | Ranger Bob |
 John SnyderHank | Hank |
 Biff YeagerBartender | Bartender |
 Lin ShayeCeleste | Celeste |
 Bill CobbsOscar | Oscar |
| SSonna ChavezAngie Abbott | Angie Abbott |
| MManny ChevroletToo Free Stooges | Too Free Stooges |
 Dick RudeToo Free Stooges | Too Free Stooges |
| TTony RuglioToo Free Stooges | Too Free Stooges |
| BBilly FerrickToo Free Stooges | Too Free Stooges |
 FleaToo Free Stooges | Too Free Stooges |
| PPete WeissToo Free Stooges | Too Free Stooges |