A reality TV crew charter a boat to an island for filming, one which the boat's captain had been to before and attacked by giant shrews, more than fifty years earlier.
| Actor | Role |
|---|---|
 John SchneiderJohnny Reno | Johnny Reno |
 Sean FlynnDerek | Derek |
 James BestThorne Sherman | Thorne Sherman |
 Bruce DavisonJerry Farrell | Jerry Farrell |
 Rick HurstHarold Rook | Harold Rook |
 Jeneta St. ClairJulie | Julie |
 Jennifer LyonsMickey | Mickey |
 Katherine RandolphLenora Mallard | Lenora Mallard |
 Jason-Shane ScottSam | Sam |
 Christopher GoodmanWillard | Willard |
 Maggie WagnerStella | Stella |
| MMegan RebeloTaylor | Taylor |
| JJason NgChuck | Chuck |
| PPatrick MoranWally | Wally |
| JJohn Anthony WilliamsHarold Rook Sr | Harold Rook Sr |
| CCollin HurstBobby | Bobby |
| BBilly TowersErnie | Ernie |
| PPatty BrowningIntern | Intern |
| DDavid BrowningNeavis | Neavis |
| JJohn Q. WilliamsHector | Hector |