 John WayneThomas Dunson | Thomas Dunson |
 Montgomery CliftMatthew Garth | Matthew Garth |
 Joanne DruTess Millay | Tess Millay |
 Walter Brennan'Groot' Nadine | 'Groot' Nadine |
 Coleen GrayFen | Fen |
 Harry CareyMr. Melville | Mr. Melville |
 John IrelandCherry Valance | Cherry Valance |
 Noah Beery Jr.Buster McGee | Buster McGee |
 Harry Carey, Jr.Dan Latimer | Dan Latimer |
 Chief YowlachieQuo | Quo |
 Paul FixTeeler Yacey | Teeler Yacey |
 Hank WordenSimms Reeves | Simms Reeves |
 Mickey KuhnMatt, as a Boy | Matt, as a Boy |
 Ray HykeWalt Jergens | Walt Jergens |
 Hal TaliaferroOld Leather | Old Leather |
| JJohn BoseDunston Rider (uncredited) | Dunston Rider (uncredited) |
| BBuck BuckoCowhand (uncredited) | Cowhand (uncredited) |
| RRoy BuckoCowhand (uncredited) | Cowhand (uncredited) |
 Lane ChandlerColonel (uncredited) | Colonel (uncredited) |
 Davison ClarkMr. Meeker (uncredited) | Mr. Meeker (uncredited) |
| TTex CooperWagon Train Member (uncredited) | Wagon Train Member (uncredited) |
 Harry CordingGambler (uncredited) | Gambler (uncredited) |
| VVictor CoxCowhand (uncredited) | Cowhand (uncredited) |
 Richard FarnsworthDunston Rider (uncredited) | Dunston Rider (uncredited) |
 Paul FierroFernandez (uncredited) | Fernandez (uncredited) |
 Carol HenryCowhand (uncredited) | Cowhand (uncredited) |
 George LloydRider with Melville (uncredited) | Rider with Melville (uncredited) |
 Pierce LydenColonel's Trail Boss (uncredited) | Colonel's Trail Boss (uncredited) |
| FFrank MeredithTrain Engineer (uncredited) | Train Engineer (uncredited) |
 John MertonSettler (uncredited) (uncredited) | Settler (uncredited) (uncredited) |
