 Dwayne JohnsonJohn Hartley | John Hartley |
 Ryan ReynoldsNolan Booth | Nolan Booth |
 Gal GadotSarah Black / The Bishop | Sarah Black / The Bishop |
 Ritu AryaInspector Urvashi Das | Inspector Urvashi Das |
 Chris DiamantopoulosSotto Voce | Sotto Voce |
 Ivan MbakopTambwe | Tambwe |
 Vincenzo AmatoDirector Gallo | Director Gallo |
 Rafael PetardiSecurity Chief Ricci | Security Chief Ricci |
 Seth MichaelsSouvenir Stand Owner | Souvenir Stand Owner |
| SSebastien LargeGelato Truck Driver | Gelato Truck Driver |
 Guy NardulliMuseum Reporter / Italian VIP | Museum Reporter / Italian VIP |
 Andrew HunterMoped Tourist | Moped Tourist |
 George TsaiBali Van Driver | Bali Van Driver |
 Rawson Marshall ThurberExhausted Film Director in Bar | Exhausted Film Director in Bar |
| RRobert MataHandsome Bartender | Handsome Bartender |
 Anthony BelevtsovPrison Guard Sergeant | Prison Guard Sergeant |
 Daniel BernhardtDrago Grande | Drago Grande |
| YYosef PodolskiLead Guard | Lead Guard |
 Martin HarrisTower Guard | Tower Guard |
 Alexander PerkinsIntelligence Analyst | Intelligence Analyst |
 Joseph A. GarciaOld Tech | Old Tech |
| GGonzalo EscuderoHead Waiter | Head Waiter |
| JJay RomeroSotto Vocce Display Room Guard | Sotto Vocce Display Room Guard |
 Ethan HerschenfeldAranoub Magdy | Aranoub Magdy |
 Brenna Marie NarayanCleopatra | Cleopatra |
 Tom ChoiMongolian Captain | Mongolian Captain |
 Nick ArapoglouOfficer on Yacht | Officer on Yacht |
 Robert ClotworthyOpening Narrator (voice) | Opening Narrator (voice) |
 Ed SheeranEd Sheeran (uncredited) | Ed Sheeran (uncredited) |
 Steve EifertPrison Captain (uncredited) | Prison Captain (uncredited) |
