The anthology film R246 Story centers around the major Japanese highway Route 246. Originating in Chiyoda Ward's Miyakezaka district, the 122.7 kilometers long Route 246 passes through Japanese trendsetting areas such as Aoyama, Omotesando, Harajuku, and Shibuya, on its way to Numazu City in Shizuoka Prefecture.
| Actor | Role |
|---|---|
 Genki SudoNot listed | Not listed |
 Kanji TsudaNot listed | Not listed |
 Hidekazu MashimaNot listed | Not listed |
 Takuya IshidaNot listed | Not listed |
 HaruNot listed | Not listed |
 Sow HirosawaNot listed | Not listed |
 Shido NakamuraNot listed | Not listed |
 Koji MatobaNot listed | Not listed |
 Ren OsugiNot listed | Not listed |
 Yuri Nakamuraおふみ | おふみ |
 Hiromi NagasakuNot listed | Not listed |
 Yusuke SantamariaNot listed | Not listed |
 Kenta HamanoNot listed | Not listed |
 Tadanobu AsanoNot listed | Not listed |
 Ryo KaseNot listed | Not listed |
| AAyane OmoriNot listed | Not listed |
 Hirofumi AraiNot listed | Not listed |
 Kosuke ToyoharaNot listed | Not listed |
 Masatoshi NagaseNot listed | Not listed |
 Tsuyoshi MuroNot listed | Not listed |