When brilliant surgeon Ukyo Retsu removes a cancer from a mysterious old woman, he doesn't realize that the cancer is a 5000 year-old demon. Ukyo must then assume the role of protector of the Earth.
| Actor | Role |
|---|---|
 Hideyuki TanakaUkyo Retsu (voice) | Ukyo Retsu (voice) |
 Hiromi TsuruFuyuko Asahina (voice) | Fuyuko Asahina (voice) |
 Shigeru ChibaProf. Takase (voice) | Prof. Takase (voice) |
| JJunko HagimoriShun-Min (Nun) (voice) | Shun-Min (Nun) (voice) |
 Daisuke GoriDemon of Earth (voice) | Demon of Earth (voice) |
 Shin MoriAssistant #1 (voice) | Assistant #1 (voice) |
 Ikuya SawakiDemon of Water (voice) | Demon of Water (voice) |
 Ryuji SaikachiElder (voice) | Elder (voice) |