In the hospital, Vince, a womanizer, is comatosed and mistakes Cristina as his guardian angel when he sees her as he opened his eyes. Little did he know that Cristina nearly killed him when she accidentally pulled his life plug. When he got well, he vowed to treat women better and find his guardian angel. One day, Cristina sees Vince with his friends. Cristina was so happy and relieved to see him alive that she hit him on the head. When Vince saw his ‘guardian angel,’ he tracked her down to get to know her better.
| Actor | Role |
|---|---|
 Aga MuhlachVince | Vince |
 Regine VelasquezCristina | Cristina |
 Bobby AndrewsBert | Bert |
 Robert ArevaloPapa | Papa |
 Sherilyn Reyes-TanAnnie | Annie |
 Bojo MolinaVictor | Victor |
 Charlie DavaoMr. Pascual | Mr. Pascual |
 Evangeline PascualMrs. Pascual | Mrs. Pascual |
| RRicci OcampoKrystal | Krystal |
 Lui ManansalaKrystal's Mother | Krystal's Mother |
| DDencio Padilla Jr.Jun | Jun |
| MMarie BarbacuiDaphne | Daphne |
 Rufa Mae QuintoPeachy | Peachy |
| JJayaNot listed | Not listed |
| TTrinity M. StilesDita | Dita |