Donna Lee Shelby, a mentally challenged girl who lives in Forest Haven, an institution for the developmentally disabled, meets Ricardo Thornton, a fellow resident. When Forest Haven is closed by a court order, Donna and Ricardo venture into the real world on their own.
| Actor | Role |
|---|---|
 Kirstie AlleyDonna Lee Shelby Thornton | Donna Lee Shelby Thornton |
 Delroy LindoRicardo Thornton | Ricardo Thornton |
 Rosemary DunsmoreCharlotte Johnson | Charlotte Johnson |
 Kevin DuhaneyRicky | Ricky |
 Catherine FitchMargaret | Margaret |
| AAnna Mary WilsonDonna as Teen | Donna as Teen |
 Brittany BristowMargaret as Teen | Margaret as Teen |
| TTerence MathewsRicardo as Teen | Ricardo as Teen |
| DDanielle BouffardDonna as Kid | Donna as Kid |
| GGary WilsonRicardo as Kid | Ricardo as Kid |
| AAnastasia HillEarline | Earline |
 Rothaford GrayBruce | Bruce |
| VVictoria AdilmanDr. Aoki | Dr. Aoki |
| NNeville EdwardsGarmin Watkins | Garmin Watkins |
 Martha BurnsDr. Maswell | Dr. Maswell |
 Patrice GoodmanSupermarket Cashier | Supermarket Cashier |
 Jane LukDr. Pearl Judd | Dr. Pearl Judd |
 Maria VacratsisHemlock Nurse | Hemlock Nurse |
 Paul Sun-Hyung LeeDelivery Doctor | Delivery Doctor |
 Katherine EastElliot Buillding Staff Worker #1 | Elliot Buillding Staff Worker #1 |
 Marium CarvellForest Haven Staff Worker | Forest Haven Staff Worker |