College student Lucy and her friends spend their vacation at her family's home in Hawaii, which includes her pet chimpanzee, Ben. However, when Ben contracts rabies after being bitten by a rabid animal, the group must fight for their lives in order to avoid the now-violent chimp.
| Actor | Role |
|---|---|
 Johnny SequoyahLucy | Lucy |
 Jessica AlexanderHannah | Hannah |
 Troy KotsurAdam | Adam |
 Victoria WyantKate | Kate |
 Gia HunterErin | Erin |
 Benjamin ChengNick | Nick |
 Charlie MannDrew | Drew |
 Tienne SimonBrad | Brad |
 Miguel Hernando Torres UmbaBen | Ben |
| AAmina AbdiSusan | Susan |
 Robin ChalkInterpreter | Interpreter |
 Joe AbercrombieBook Publisher | Book Publisher |
| NNick RomanoPolice Officer | Police Officer |
 Ben PronskyBen (voice) (uncredited) | Ben (voice) (uncredited) |
 Rob DelaneyDoc Lambert (uncredited) | Doc Lambert (uncredited) |
 Kae AlexanderMother (uncredited) | Mother (uncredited) |
 Stuart WhelanPassenger (uncredited) | Passenger (uncredited) |