In this sequel to the acclaimed videogame comedy PRESS START, the world's most inexplicably accomplished evil sorcerer, Count Vile, has returned from Hades for a new bid at global domination. With original champions Zack and Sam already in his clutches, it's up to their estranged, ultraviolent comrade Lin-Ku and the bubbly, positive-thinking Princess Xanna to save them – and the world – from disaster. PRESS START 2 CONTINUE also adds fan favorite characters from the "Press Start Adventures" animated web series including the sardonic vampire lord Vlad (David S. Humphrey, Sonic Adventure 2 & Jack Keane), sinister succubus Morgan Le Slay, and white-haired assassin Scarthcaroth. Web personalities Noah Antwiler, Stuart Ashen, Lindsey "Z" Briggs, and X-Strike Studios' Tim Ekkebus & Rory O’Boyle also join the cast.
| Actor | Role |
|---|---|
| JJoshua StaffordZack Nimbus | Zack Nimbus |
| AAl MorrisonLin-Ku | Lin-Ku |
 Peter A. DavisCount Nefarious Vile | Count Nefarious Vile |
| JJenny NelsonPrincess Xanna | Princess Xanna |
| JJennifer ZahnSam | Sam |
 J.W. MorrissetteJohnson | Johnson |
 David HumphreyVlad (Voice) | Vlad (Voice) |
 Dominique WorsleySpanish Ninja | Spanish Ninja |
 Arin HansonMug-Wug (voice) | Mug-Wug (voice) |
 Jane F. CoxMorgan Le Slay | Morgan Le Slay |
 Andy DallasShopkeeper | Shopkeeper |
 Eric W. SizemoreGame Genie | Game Genie |
| MMarty ScanlonScarthcaroth | Scarthcaroth |
 Noah AntwilerP.O.L.I.G.A.M.O.N. (voice) | P.O.L.I.G.A.M.O.N. (voice) |
 Stuart AshenV-Corp Announcer (voice) | V-Corp Announcer (voice) |
 Alex MitchellSchizoid Cricket | Schizoid Cricket |
| IIain CarpenterPaperboy | Paperboy |
 George NowikGilgamoth / King Sing Song (voice) | Gilgamoth / King Sing Song (voice) |
| TTim EkkebusBuddy 1 (voice) | Buddy 1 (voice) |