When Pollyanna is orphaned, she's sent to live with her crotchety Aunt Polly. Pollyanna discovers that many of the people in her aunt's New England hometown are as ill-tempered as her aunt. But Pollyanna's incurable optimism - exemplified by her "glad game", in which she looks for the bright side of every situation - brings a change to the staid old community.
| Actor | Role |
|---|---|
 Mary PickfordPollyanna Whittier | Pollyanna Whittier |
 Katherine GriffithAunt Polly Harrington | Aunt Polly Harrington |
| HHoward RalstonJimmy Bean | Jimmy Bean |
 Helen Jerome EddyNancy Thing | Nancy Thing |
 George BerrellOld Tom | Old Tom |
 William CourtleighJohn Pendleton | John Pendleton |
 Herbert PriorDr. Tom Chilton | Dr. Tom Chilton |
| WWharton JamesRev. John Whittier | Rev. John Whittier |
| DDoc CraneBit Role (uncredited) | Bit Role (uncredited) |
 Joan MarshBit Role (uncredited) | Bit Role (uncredited) |
 Frederick PetersBit Role (uncredited) | Bit Role (uncredited) |
 Gordon SackvilleBit Role (uncredited) | Bit Role (uncredited) |