In 2020, DCI Billy O'Connell is tasked with tackling an armed suspect who takes a group of Russian immigrants hostage in a lift after blaming the immigrant population for an outbreak of tuberculosis that killed most of his family
| Actor | Role |
|---|---|
 Liam CunninghamDCI Billy O'Connell | DCI Billy O'Connell |
 Rachel DaviesDCI Marsha Beagley | DCI Marsha Beagley |
| NNick RedingDS Keanan | DS Keanan |
 Saira ToddKatline Voikevich | Katline Voikevich |
 Keith BarronEddie Longshaw | Eddie Longshaw |
 Ken BonesCommander Johnson | Commander Johnson |
 Ken BradshawDS Dewhurst | DS Dewhurst |
 Tim DantayDI Brian Sagar | DI Brian Sagar |
| SStephen HackettDS Steven Springfield | DS Steven Springfield |
 Esther HallJulie Ostrovsky | Julie Ostrovsky |
 Velibor TopicMikki Ostrovsky | Mikki Ostrovsky |
 Andrew KnottScully | Scully |
 Jane SlavinDC Fiona Muir | DC Fiona Muir |
| DDavid ProshoDr Fortnum | Dr Fortnum |
 Maureen HibbertDI Christine Baker | DI Christine Baker |
| IIvan MarevichAndreyev | Andreyev |
 Rad LazarUri | Uri |
| JJames MastersScreen Commander | Screen Commander |
 Shaun McGowanDesk Sergeant | Desk Sergeant |
| GGriff HarriesTramp | Tramp |
| JJonathan DahlRussian Youth | Russian Youth |
| HHelen GraysonRussian Immigrant (as China-Black) | Russian Immigrant (as China-Black) |