The body of a homeless man is found in Cologne not in the Dark Ages, but in the year 2000, where an autopsy reveals that he died of the plague. Doctor Martin Brügger sets out to find the cause and discovers masses of dead rats in the sewers. The population of the Rhine metropolis is in danger - but the authorities do not want to cause panic and keep the case a secret.
| Actor | Role |
|---|---|
 Tim BergmannDr. Clemens Lindenthal | Dr. Clemens Lindenthal |
 Dietmar BärBoccacio | Boccacio |
 Hannelore HogerBürgermeisterin | Bürgermeisterin |
 Dietrich HollinderbäumerDr. Salomon | Dr. Salomon |
 Ralph HerforthNot listed | Not listed |
 Katy KarrenbauerNot listed | Not listed |
 Jan-Gregor KrempBruder Tankred | Bruder Tankred |
 Jochen NickelWilli | Willi |
 Thomas SarbacherDr. Martin Brügger | Dr. Martin Brügger |
 Antje SchmidtDr. Verena Franke | Dr. Verena Franke |
 Oliver BootzNot listed | Not listed |
| SStephan DellgrünSven | Sven |
 Max GertschNot listed | Not listed |
| SSiggi KautzNot listed | Not listed |
 Ernst H. HilbichNot listed | Not listed |