Recounts the extraordinary segregation-era partnership between two surgeons--one black and one white--who defied the medical establishment and changed the course of cardiac surgery.
| Actor | Role |
|---|---|
 Morgan FreemanNarrator (voice) | Narrator (voice) |
 Alfred BlalockSelf (archive footage) | Self (archive footage) |
 Vivien ThomasSelf (archive footage) | Self (archive footage) |
| CChristopher HaleyVivien Thomas | Vivien Thomas |
| BBeau JamesAlfred Blalock | Alfred Blalock |
 Courtney B. VanceVivien Thomas (voice) | Vivien Thomas (voice) |