"Mary Meacham, the most popular girl in college, goes to live with her maiden aunt, Miss Myra. Auntie is a man-hater who has various theories for testing the desirable qualities of the male sex. Mary sees a dreary man-less time before her and sends an S. O. S. to various sisters and their brothers to visit her while Auntie is away.
| Actor | Role |
|---|---|
 Madge KennedyMary Meacham | Mary Meacham |
 Marguerite MarshSusie | Susie |
 Harry MyersBobby Burns | Bobby Burns |
| GGeorge J. ForthMorgan Smith | Morgan Smith |
 Kate LesterKathleen McEchran | Kathleen McEchran |
| GGeorge StevensJudge Adams | Judge Adams |
| BBernard ThorntonDick Lester | Dick Lester |
| AA. DrehleDr. Chase | Dr. Chase |
| HHarry FrazerProfessor Putnam | Professor Putnam |
| DDixie ThompsonLuke | Luke |
| MMay RogersNellie Burns | Nellie Burns |
 Marcia HarrisMyra Meacham | Myra Meacham |