 Steve MartinFrank Sangster | Frank Sangster |
 Helena Bonham CarterSusan | Susan |
 Laura DernJean Noble | Jean Noble |
 Lynne ThigpenPat | Pat |
 Chelcie RossMike | Mike |
 Polly NoonanSally | Sally |
 JoBe CernyPharmacist Wayne Ponze | Pharmacist Wayne Ponze |
 Elias KoteasHarlan Sangster | Harlan Sangster |
 Yasen Peyankov'Sunshine Lounge' Bartender | 'Sunshine Lounge' Bartender |
 Scott CaanDuane | Duane |
| TTeri CotruzzolaAttractive Complaining Patient | Attractive Complaining Patient |
 Lucina PaquetMrs. Langston | Mrs. Langston |
 Preston MaybankGelding | Gelding |
| SSally KaoChinese Wife | Chinese Wife |
| QQuincy WongChinese Husband | Chinese Husband |
| GGeorge LuggLiquor Store Owner | Liquor Store Owner |
| TTyler RostenkowskiBilly | Billy |
 Tom Milanovich'Blue Sands' Bartender | 'Blue Sands' Bartender |
 Karol KentDetective Lily Pons | Detective Lily Pons |
 Keith DavidDetective Lunt | Detective Lunt |
 Eddie Bo Smith Jr.Motel Security Guard | Motel Security Guard |
 Mary Ann ChildersAnchorwoman | Anchorwoman |
 Rich KomenichDetective | Detective |
| JJames ChisemHarris | Harris |
 Joseph F. KosalaOfficer Peter Reilly | Officer Peter Reilly |
 Eric LaneOfficer Chuck Smith | Officer Chuck Smith |
| RRoy HytowerSkinny Sheriff | Skinny Sheriff |
 Kwame AmoakuVisiting Room Guard | Visiting Room Guard |
 Christian StolteCourt Guard | Court Guard |
| LLen BajenskiTrooper Jarvis | Trooper Jarvis |
