"Daijobu 3 Kumi" depicts the interactions between new teacher Shinnosuke Akao, who was born without arms and legs, and the 28 students in his 5th grade class, told from the vantage point of school board member Yusaku Shiraishi
| Actor | Role |
|---|---|
 Taichi KokubunYusaku Shiraishi | Yusaku Shiraishi |
| HHirotada OtotakeShinnosuke Akao | Shinnosuke Akao |
 Nana EikuraMiyuki Sakamoto | Miyuki Sakamoto |
 Hiroki MiyakeTakashi Konno | Takashi Konno |
 Tamae AndoHideko Aoyanagi | Hideko Aoyanagi |
 Tomorowo TaguchiShinichi Haitani | Shinichi Haitani |
 Kimiko YoChieko Kuroki | Chieko Kuroki |
 Momoko TanabeKyoko Ando | Kyoko Ando |
| HHonoka AsadaHonoka | Honoka |
 Yuna TairaSatoko Chiba | Satoko Chiba |
 Mone KamishiraishiAyano Nakanishi | Ayano Nakanishi |
| YYumi EndoYumi Maezono | Yumi Maezono |
 Nanami HinataNanami Miura | Nanami Miura |
 Makiko WatanabeAyano's mother | Ayano's mother |
 Houka KinoshitaAyano's father | Ayano's father |
 Toshie NegishiShinnosuke's mother | Shinnosuke's mother |