 John LiuJohn Liu / The Ninja | John Liu / The Ninja |
 Don WilsonJohn Liu / The Ninja (voice) | John Liu / The Ninja (voice) |
 Adrienne MeltzerRandi Rydell | Randi Rydell |
 Linnea QuigleyRandi Rydell (voice) | Randi Rydell (voice) |
 Vince MurdoccoJack "The Cameraman" (voice) | Jack "The Cameraman" (voice) |
 Leon Isaac KennedyDet. Jimmy Williams (voice) | Det. Jimmy Williams (voice) |
 Cynthia RothrockDet. Janet Flores (voice) | Det. Janet Flores (voice) |
 Michael BerrymanThe Plutonium Killer (voice) | The Plutonium Killer (voice) |
 Matt MitlerFreddy Cufflinks (voice) | Freddy Cufflinks (voice) |
 Ginger Lynn AllenNita Liu (voice) | Nita Liu (voice) |
 Zihan ZhaoThe Kid (voice) | The Kid (voice) |
 Bill TimoneyThe Pale Man (voice) | The Pale Man (voice) |
| DDarius ChurchmanRicco (voice) | Ricco (voice) |
| RRobb MoreiraThe Mayor (voice) | The Mayor (voice) |
 Tom WaylandSwitchblade (voice) | Switchblade (voice) |
 Lee BaptisteStreet Lion (voice) | Street Lion (voice) |
| RRichard Buckingham ClarkRattail | Rattail |
 Wayne GraysonRattail (voice) | Rattail (voice) |
 Ryan AndesAdditional Voice (voice) | Additional Voice (voice) |
| DDan BeckerAdditional Voice (voice) | Additional Voice (voice) |
| NNicholas CordaAdditional Voice (voice) | Additional Voice (voice) |
 Hollis FoxAdditional Voice (voice) | Additional Voice (voice) |
 Mike PollockAdditional Voice (voice) | Additional Voice (voice) |
| SSarah SmithtonAdditional Voice (voice) | Additional Voice (voice) |
 Lori Gardner PhillipsAdditional Voice (voice) | Additional Voice (voice) |
 Barrett LeddyAdditional Voice (voice) | Additional Voice (voice) |
| BBen WaylandAdditional Voice (voice) | Additional Voice (voice) |
| FFinn WaylandAdditional Voice (voice) | Additional Voice (voice) |
 Sharon MitchellWoman on Train (uncredited) | Woman on Train (uncredited) |
 Robert TuranoMan on Train (uncredited) | Man on Train (uncredited) |
