Picking up after the events of Never Back Down 2, former MMA champion Case Walker is on the comeback trail to become champion once again.
| Actor | Role |
|---|---|
 Michael Jai WhiteCase Walker | Case Walker |
 Josh BarnettBrody James | Brody James |
 Gillian WhiteMyca Cruz | Myca Cruz |
 Nathan JonesCaesar Braga | Caesar Braga |
| DDamian MavisCage Fighter | Cage Fighter |
| AAaron BrumfieldBoris | Boris |
 Elidh MacQueenHottie | Hottie |
| CCreighton Mark JohnsonTrainer (as Creighton Mark Johnsom) | Trainer (as Creighton Mark Johnsom) |
 Eoin O'BrienCobra O'Conor | Cobra O'Conor |
| GGreg Matt GarciaCamera Guy | Camera Guy |
| DDan RenaldsCreech | Creech |
 JeeJa YaninJeeJa - Gym Fighter Girl | JeeJa - Gym Fighter Girl |
 Esai MoralesHugo Vega | Hugo Vega |
 Stephen QuadrosMatty Ramos | Matty Ramos |
 Brahim AchabbakheBrody's Young Pro Fighter | Brody's Young Pro Fighter |
 Ron SmoorenburgCase's 1st Fight Opponent | Case's 1st Fight Opponent |
 Tony JaaTony Jaa | Tony Jaa |
 Quinton 'Rampage' JacksonPampage | Pampage |