When Champion City's hero Captain Amazing is kidnapped by the recently paroled supervillain Casanova Frankenstein, a trio of average, everyday superheroes -- Mr. Furious, the Shoveler and the Blue Raja -- assemble a new super team to save him.
| Actor | Role |
|---|---|
 Ben StillerMr. Furious / Roy | Mr. Furious / Roy |
 Hank AzariaBlue Raja / Jeffrey | Blue Raja / Jeffrey |
 William H. MacyShoveler / Eddie | Shoveler / Eddie |
 Greg KinnearCaptain Amazing / Lance | Captain Amazing / Lance |
 Kel MitchellInvisible Boy | Invisible Boy |
 Paul ReubensSpleen | Spleen |
 Janeane GarofaloBowler / Carol | Bowler / Carol |
 Wes StudiSphinx | Sphinx |
 Claire ForlaniMonica | Monica |
 Geoffrey RushCasanova Frankenstein | Casanova Frankenstein |
 Lena OlinDr. Anabel Leek | Dr. Anabel Leek |
 Suzy Eddie IzzardTony P | Tony P |
 Tom WaitsDoc Heller | Doc Heller |
 Artie LangeBig Red | Big Red |
 Louise LasserViolet | Violet |
 Ricky JayVic Weems | Vic Weems |
 Jenifer LewisLucille | Lucille |
 Pras MichelTony C | Tony C |
 Ned BellamyFunk | Funk |
 Joel McCraryMcGuire | McGuire |
 Ernie Lee BanksTed | Ted |
 Gerry BeckerBanyon | Banyon |
 Corbin BleuButch | Butch |
 Philip BoldenRoland | Roland |
 Jake CrossThug | Thug |
 Emmy LaybourneReporter | Reporter |
 Mason LuceroYoung Kid | Young Kid |
 Monet MazurBecky Beaner | Becky Beaner |
| CChristopher MugglebeeReporter | Reporter |
| OOlivia Lauren ToddTracy | Tracy |