An escaped serial killer and an attempt on Travis's life makes this their most dangerous case yet as Amy and Travis team up with his FBI agent ex to find the connection before it's too late.
| Actor | Role |
|---|---|
 Jill WagnerProfessor Amy Winslow | Professor Amy Winslow |
 Kristoffer PolahaDetective Travis Burke | Detective Travis Burke |
 Preston VandersliceBud | Bud |
 Robin ThomasGraham Winslow | Graham Winslow |
 Michelle Choi-LeeApril Welker | April Welker |
 Charles JarmanJudge | Judge |
 Blake StadelJoe Gearon | Joe Gearon |
 Erin CahillKate | Kate |
 Miranda EdwardsMaria Valdez | Maria Valdez |
 Shiraine HaasRita Goff | Rita Goff |
 Daniel BaconMel Goff | Mel Goff |
 Adrian PetriwJeffrey Lewandowski | Jeffrey Lewandowski |
 Lossen ChambersTabitha Felton | Tabitha Felton |
 Fred KeatingBill Breyer | Bill Breyer |
| JJulie HowgateEva Bianco | Eva Bianco |
 Amira AndersonEMT | EMT |
 Bronwen SmithPresident Rivers | President Rivers |
| CCassandra Constance BolinskiNurse | Nurse |
 Chad RileyAlberto | Alberto |
 Todd MannDarren Ellis | Darren Ellis |
 Brad MannDavid Ellis | David Ellis |
 Tanya ChampouxDiedre Breyer | Diedre Breyer |
| MMartin Renner WallaceLarry | Larry |