 Jacob TremblayElmer Elevator (voice) | Elmer Elevator (voice) |
 Golshifteh FarahaniDela Elevator (voice) | Dela Elevator (voice) |
 Gaten MatarazzoBoris the Dragon (voice) | Boris the Dragon (voice) |
 Dianne WiestIris the Rhinoceros (voice) | Iris the Rhinoceros (voice) |
 Rita MorenoMrs. McClaren (voice) | Mrs. McClaren (voice) |
 Chris O'DowdKwan the Macaque (voice) | Kwan the Macaque (voice) |
 Judy GreerSoda the Whale (voice) | Soda the Whale (voice) |
 Alan CummingCornelius the Crocodile (voice) | Cornelius the Crocodile (voice) |
 Yara ShahidiCallie (voice) | Callie (voice) |
 Jackie Earle HaleyTamir the Tarsier (voice) | Tamir the Tarsier (voice) |
 Mary Kay PlaceNarrator (voice) | Narrator (voice) |
 Leighton MeesterSasha (voice) | Sasha (voice) |
 Spence Moore IIGeorge (voice) | George (voice) |
 Adam BrodyBob (voice) | Bob (voice) |
 Lo MutucMagda (voice) | Magda (voice) |
 Jack S. A. SmithEugene (voice) | Eugene (voice) |
| MMaggie LincolnGertie (voice) | Gertie (voice) |
 Whoopi GoldbergCat (voice) | Cat (voice) |
 Ian McShaneSaiwa (voice) | Saiwa (voice) |
 Debi DerryberryAdditional voices (voice) | Additional voices (voice) |
 Skip StellrechtAdditional voices (voice) | Additional voices (voice) |
 Hope LevyAdditional Voices (voice) | Additional Voices (voice) |
| TTerence Matthews IIAdditional voices (voice) | Additional voices (voice) |
| AAnnabel LewAdditional voices (voice) | Additional voices (voice) |
 Andrew MorgadoAdditional voices (voice) | Additional voices (voice) |
 Jim PirriAdditional voices (voice) | Additional voices (voice) |
| JJon OlsonAdditional voices (voice) | Additional voices (voice) |
| CCat RingAdditional voices (voice) | Additional voices (voice) |
 Fred TatascioreAdditional voices (voice) | Additional voices (voice) |
 Michelle RuffAdditional voices (voice) | Additional voices (voice) |
