Based on the "Saturday Night Live" shorts, Mr. Bill stars in his own show, but this time he's played by a human actor.
| Actor | Role |
|---|---|
 Peter ScolariMr. Bill | Mr. Bill |
 Valerie MahaffeyMrs. Bill | Mrs. Bill |
| MMichael McManusSluggo | Sluggo |
 Lenore KasdorfMrs. Sluggo | Mrs. Sluggo |
| CChristopher BurtonBilly | Billy |
| HHope TibbettsJunior | Junior |
 Shelley DuvallSelf | Self |