 Kate HigginsFrankie Stein (voice) | Frankie Stein (voice) |
 Debi DerryberryDraculaura (voice) | Draculaura (voice) |
 Salli SaffiotiClawdeen Wolf / Cleo de Nile (voice) | Clawdeen Wolf / Cleo de Nile (voice) |
 Laura BaileyLagoona Blue (voice) | Lagoona Blue (voice) |
 Erin FitzgeraldAbbey Bominable / C.A. Cupid / Rochelle Goyle / Spectra (voice) | Abbey Bominable / C.A. Cupid / Rochelle Goyle / Spectra (voice) |
 Ogie BanksClawd Wolf (voice) | Clawd Wolf (voice) |
 Evan SmithDeuce Gorgon / Gil Webber / Bram Devein / Rocco (voice) | Deuce Gorgon / Gil Webber / Bram Devein / Rocco (voice) |
 Audu PadenGhoulia Yelps / Manny Taur / Announcer / Nightmare (voice) | Ghoulia Yelps / Manny Taur / Announcer / Nightmare (voice) |
 America YoungToralei / Howleen Wolf (voice) | Toralei / Howleen Wolf (voice) |
 Julie MaddalenaRobecca Steam / Venus McFlytrap (voice) | Robecca Steam / Venus McFlytrap (voice) |
 Cam ClarkeHeath Burns / Romulus (voice) | Heath Burns / Romulus (voice) |
 Cindy RobinsonJackson Jekyll / Operetta (voice) | Jackson Jekyll / Operetta (voice) |
 Andrew DuncanGary (voice) | Gary (voice) |
| IIra SingermanEye-ra (voice) | Eye-ra (voice) |
