To free Baba Yaga and Renfield from the clutches of Monster Hunter Mila Starr, the Wishbone Family once more transforms into a Vampire, Frankenstein's Monster, a Mummy and a Werewolf but when aided by their three pet bats, the Monster Family zooms around the world again to save their friends, make new monstrous acquaintances.
| Actor | Role |
|---|---|
 Emily WatsonEmma Wishbone (voice) | Emma Wishbone (voice) |
 Nick FrostFrank Wishbone (voice) | Frank Wishbone (voice) |
 Jessica Brown FindlayFay Wishbone (voice) | Fay Wishbone (voice) |
 Ethan RouseMax Wishbone (voice) | Max Wishbone (voice) |
 Jason IsaacsDracula (voice) | Dracula (voice) |
 Catherine TateBaba Yaga (voice) | Baba Yaga (voice) |
 Emily CareyMila Starr (voice) | Mila Starr (voice) |
 Daniel Ben ZenouMaddox Starr (voice) | Maddox Starr (voice) |
 Emma TateMarlene Starr / Girl #2 / Newscaster (voice) | Marlene Starr / Girl #2 / Newscaster (voice) |
 Ewan BaileyReinfield / Reverend / Fisherman / Newscaster / Farmer (voice) | Reinfield / Reverend / Fisherman / Newscaster / Farmer (voice) |
| RRebecca KampGirl #1 (voice) | Girl #1 (voice) |