Drs. Hayes and Lincoln are researchers in biological oddities for the Humanidyne company. When they find a man still alive after being frozen for 50 years, their greedy boss fires them and takes the Iceman to use for military experiments. Left without jobs, Hayes and Lincoln decide to get a group of "freaks" (including a telekinetic 17-year-old and a rock guitarist who shoots lightning from his hands) together to rescue the Iceman and stop their boss' reckless experiments.
| Actor | Role |
|---|---|
 Dean Paul MartinDr. Billy Hayes | Dr. Billy Hayes |
 Kevin Peter HallDr. Elvin 'El' Lincoln | Dr. Elvin 'El' Lincoln |
 Mark Thomas MillerJohn 'Johnny B' Bukowski | John 'Johnny B' Bukowski |
 Courteney CoxGloria Dinallo | Gloria Dinallo |
 Mickey JonesArnold Biefneiter | Arnold Biefneiter |
 Jennifer HolmesJane Miller | Jane Miller |
 Eric ChristmasDr. Momquist | Dr. Momquist |
 Larry LinvilleGen. Theil | Gen. Theil |
| DDiane CaryMiss Nance | Miss Nance |
 Tawny LittleReporter | Reporter |
 Leslie EasterbrookStrickland's Secretary | Strickland's Secretary |
 Edward WinterDr. James Strickland | Dr. James Strickland |
 Kenneth MarsSen. Donner | Sen. Donner |
 Bert RosarioGomez | Gomez |
| RRobert StarrStenker | Stenker |
 K.C. WinklerDonna | Donna |
| PPreston HansonNewscaster | Newscaster |
| BBoyd BodwellBob Scanlon | Bob Scanlon |
 Eric FleeksAmbulance Attendant | Ambulance Attendant |
| WWendy OatesFirst Technician | First Technician |
| RRalph BrannenSecond Technician | Second Technician |
 Gerald BernsStickland's Aide | Stickland's Aide |
| DDawan ScottBallplayer | Ballplayer |