 Pierre CoffinMinions (voice) | Minions (voice) |
 Raymond S. PersiHead Elf (voice) | Head Elf (voice) |
 Carlos AlazraquiSanta / Driver / Adult Reindeer / Elves (voice) | Santa / Driver / Adult Reindeer / Elves (voice) |
 Tara StrongScouts / Shop Owner / Baby Reindeer / Elves (voice) | Scouts / Shop Owner / Baby Reindeer / Elves (voice) |
 Brian T. DelaneyMailman / Adult Reindeer / Elves (voice) | Mailman / Adult Reindeer / Elves (voice) |
 Miranda CosgroveMargo (voice) | Margo (voice) |
 Jessica DiCiccoScouts (voice) | Scouts (voice) |
 John DiMaggioScout Master (voice) | Scout Master (voice) |
 Dana Gaier EllisEdith (voice) | Edith (voice) |
 Nhev ScharrelAgnes (voice) | Agnes (voice) |
 Cory WallsGawky Teen / Additional Voices (voice) | Gawky Teen / Additional Voices (voice) |
 John KassirCoffee Shop Manager (voice) | Coffee Shop Manager (voice) |
 Benedict CumberbatchThe Grinch (voice) | The Grinch (voice) |
 Chris RenaudNorman / Pipsqueak (voice) | Norman / Pipsqueak (voice) |
 Danny MannHarold (voice) | Harold (voice) |
 Lori AlanMarilyn (voice) | Marilyn (voice) |
| KKelly LakeAdditional Voices (voice) | Additional Voices (voice) |
 Eric OsmondAdditional Voices (voice) | Additional Voices (voice) |
 Jan RabsonAdditional Voices (voice) | Additional Voices (voice) |
 Dave RosenbaumIce Cream Vendor / Additional Voices (voice) | Ice Cream Vendor / Additional Voices (voice) |
 Colette WhitakerAdditional Voices (voice) | Additional Voices (voice) |
 Elsie FisherAgnes (voice) | Agnes (voice) |
 Régis SchullerJewel Thief (voice) | Jewel Thief (voice) |
 Steve CarellGru (voice) (uncredited) | Gru (voice) (uncredited) |
 Taron EgertonJohnny (voice) | Johnny (voice) |
 Garth JenningsMiss Crawly (voice) | Miss Crawly (voice) |
 Robert MorseHerman (voice) | Herman (voice) |
| GGreg LastrapesFrank (voice) | Frank (voice) |
| SScarlet LastrapesTimmy (voice) | Timmy (voice) |
 Jim WardAdditional Voices (voice) | Additional Voices (voice) |
