Detectives Jake Doyle and Mary Kelly seek the help of an incarcerated serial killer named The Artist when a copycat killer strikes. While Mary searches for clues in The Artist's brilliant but twisted psyche, she and Jake are lured into a diabolical game of cat and mouse, racing against time to stay one step ahead of The Artist and his copycat.
| Actor | Role |
|---|---|
 Martin LawrenceJake Doyle | Jake Doyle |
 Melissa RoxburghMary Kelly | Mary Kelly |
 John MalkovichThe Artist | The Artist |
 Aiden TurnerDale | Dale |
 Jacob GrodnikDutch | Dutch |
 Chris MullinaxHomeless Man | Homeless Man |
 Ritchie MontgomeryFather Linares | Father Linares |
 Kira Reed LorschDetective Kayne | Detective Kayne |
| JJeremy TurnerThe Copycat | The Copycat |
 Cassandra GavaVoodoo Priestess | Voodoo Priestess |
| JJoshua WeatherbyConfused Boy | Confused Boy |
 Barry CliftonGuard #1 | Guard #1 |
 Victoria FoxAssistant | Assistant |
 Neb ChupinDr. Loesch | Dr. Loesch |
 Laura ShatkusThe Artist's Mother | The Artist's Mother |
 Mike StutzGuard #2 | Guard #2 |
| BBilly Ray EstesPriest | Priest |
| JJohn HoneyForensic Cop | Forensic Cop |
| BBrooke BierhausForensic Agent | Forensic Agent |
| MMark Landon SmithMr. Langdon | Mr. Langdon |
| KKatherine ForbesThe Old Lady | The Old Lady |
 Robert KnepperLt. Owings | Lt. Owings |