 Colin FarrellDet. James 'Sonny' Crockett | Det. James 'Sonny' Crockett |
 Jamie FoxxDet. Ricardo 'Rico' Tubbs | Det. Ricardo 'Rico' Tubbs |
 Naomie HarrisDet. Trudy Joplin | Det. Trudy Joplin |
 Gong LiIsabella | Isabella |
 John OrtizJosé Yero | José Yero |
 Ciarán HindsFBI Agent John Fujima | FBI Agent John Fujima |
 Justin TherouxDet. Larry Zito | Det. Larry Zito |
 Barry Shabaka HenleyLt. Martin Castillo | Lt. Martin Castillo |
 Elizabeth RodriguezDet. Gina Calabrese | Det. Gina Calabrese |
 John HawkesAlonzo Stevens | Alonzo Stevens |
 Eddie MarsanNicholas | Nicholas |
 Luis TosarArcángel de Jesús Montoya | Arcángel de Jesús Montoya |
 Domenick LombardozziDet. Stan Switek | Det. Stan Switek |
 Isaach de BankoléNeptune | Neptune |
 Tom TowlesColeman | Coleman |
 Mario Ernesto SánchezEl Tiburon | El Tiburon |
 Frankie J. AllisonDeep-Chested Aryan Brother | Deep-Chested Aryan Brother |
 Tony CurranAryan Brother | Aryan Brother |
 Stephan JonesDark-Haired Aryan Brother | Dark-Haired Aryan Brother |
| RRob LarsonLong-Haired Aryan Brother | Long-Haired Aryan Brother |
 Don FryeLong-Haired Aryan Brother | Long-Haired Aryan Brother |
| MMaxim DanilovRussian FBI Agent | Russian FBI Agent |
 Pasha D. LychnikoffRussian FBI Agent | Russian FBI Agent |
 Ana Cristina OliveiraFemale Bartender | Female Bartender |
| EEverlayn BorgesMiss Cuba | Miss Cuba |
| JJuanita BillueMiss Jamaica | Miss Jamaica |
| PPatrick Michael BuckleyAir Traffic Controller | Air Traffic Controller |
 Marc MacaulayAir Traffic Supervisor | Air Traffic Supervisor |
 Mike PniewskiER Doctor | ER Doctor |
| VVivienne SendaydiegoER Doctor | ER Doctor |
