Thomas and his fellow Gladers face their greatest challenge yet: searching for clues about the mysterious and powerful organization known as WCKD. Their journey takes them to the Scorch, a desolate landscape filled with unimaginable obstacles. Teaming up with resistance fighters, the Gladers take on WCKD’s vastly superior forces and uncover its shocking plans for them all.
| Actor | Role |
|---|---|
 Dylan O'BrienThomas | Thomas |
 Kaya ScodelarioTeresa Agnes | Teresa Agnes |
 Thomas Brodie-SangsterNewt | Newt |
 Giancarlo EspositoJorge | Jorge |
 Ki Hong LeeMinho | Minho |
 Dexter DardenFrypan | Frypan |
 Rosa SalazarBrenda | Brenda |
 Patricia ClarksonAva Paige | Ava Paige |
 Aidan GillenJanson | Janson |
 Barry PepperVince | Vince |
 Nathalie EmmanuelHarriet | Harriet |
 Alexander FloresWinston | Winston |
 Jacob LoflandAris Jones | Aris Jones |
 Lili TaylorMary Cooper | Mary Cooper |
 Alan TudykBlondie | Blondie |
 Terry Dale ParksCarl (Masked Man) | Carl (Masked Man) |
| KKathryn Smith-McGlynnDr. Crawford | Dr. Crawford |
 Matthew T. MetzlerBarkley | Barkley |
 Jenny GabriellePonytail | Ponytail |
 David HouseSoldier | Soldier |
 Lora Martinez-CunninghamThomas' Mother | Thomas' Mother |
| LLuke GallegosYoung Thomas | Young Thomas |
 Shawn PrinceDavid | David |
 Jeremy BecerraRiley | Riley |
 Matthew PageHarold (Soldier) | Harold (Soldier) |
 Alex KnightAide | Aide |
| MMarc ComstockMed Tech | Med Tech |
| JJohn TrejoM3 Soldier | M3 Soldier |
 Katherine McNamaraSonya | Sonya |
 Tatanka MeansJoe | Joe |