Boobita Rose is a woman dealing with her dysfunctional family and a socially challenged love life.
| Actor | Role |
|---|---|
 Rufa Mae QuintoBoobita Rose | Boobita Rose |
| AAntonio AquitaniaRandy | Randy |
 Sunshine DizonBrigitte | Brigitte |
 Gina PareñoLupe | Lupe |
 John LapusBogs | Bogs |
| RRudy HatfieldMark | Mark |
 Chinggoy AlonzoBoss | Boss |
 Raquel MontezaBoss' Wife | Boss' Wife |
| PPhytos RamirezBoogie | Boogie |
 Kier LegaspiLupe's Boyfriend | Lupe's Boyfriend |
 Charlie DavaoSenator | Senator |
 Regine VelasquezRegine Velasquez | Regine Velasquez |
 Ogie AlcasidOgie Alcasid | Ogie Alcasid |
 KarylleKarylle | Karylle |
| KKylaKyla | Kyla |
 Sarah GeronimoSarah Geronimo | Sarah Geronimo |
 Bituin EscalanteBituin Escalante | Bituin Escalante |
 BlakdyakBlakdyak | Blakdyak |
| LLani MisaluchaLani Misalucha | Lani Misalucha |
 Mark BautistaMark Bautista | Mark Bautista |
| AAnna FegiAnna Fegi | Anna Fegi |
| SSalbakutaSalbakuta | Salbakuta |
 Ely BuendiaEly Buendia | Ely Buendia |
 Martin NieveraMartin Nievera | Martin Nievera |